BANF2

Across TCGA pan-cancer cohorts, BANF2 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of BANF2’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where BANF2 RNA is repressed in tumor relative to normal tissue. In most cancer types BANF2 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, LIHC, and BRCA are the cancer types where BANF2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BANF2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−1.238	<.001	11	view →
LIHC	Male	All	+0.467	<.001	7	view →
BRCA	All	III,IV	−0.047	.018	6	view →
KICH	All	All	−0.082	<.001	5	view →
UCEC	All	All	−0.138	.043	2	view →
LUAD	Female	All	+0.030	.012	2	view →
KIRP	Male	All	−0.074	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

BANF2–THCA

Open the THCA breakdown →