BANF2

Across TCGA pan-cancer cohorts, BANF2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated BANF2 data layer compared with 1 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher BANF2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BANF2 expression acts as an unfavorable survival marker, although some lineages such as BRCA and CHOL show a favorable association.

LGG, BRCA, and HNSC are the cancer types where BANF2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.246	0.472	<.001	54	view →
BRCA	OS	Quartile	III,IV	0.930	0.801	.011	46	view →
HNSC	OS	Tertile	III,IV	0.287	0.583	.013	21	view →
PAAD	DFS	Tertile	III,IV	0.275	0.794	.008	20	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
THYM	OS	Tertile	All	0.608	0.894	.005	18	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.038	9	view →
CHOL	DFS	Tertile	IV	0.950	0.406	.040	9	view →
STAD	DFS	Tertile	IV	0.083	0.411	.025	6	view →
LUSC	DFS	Tertile	All	0.865	0.660	.037	6	view →
ESCA	OS	Tertile	IV	0.713	0.243	.024	6	view →
READ	DFS	Median	All	0.932	0.706	.022	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

BANF2–LGG (DFS)

Open the LGG breakdown →