BAALC-AS2

Across TCGA patient cohorts, BAALC-AS2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAALC-AS2-associated genes across cancer lineages are MIR3912, RNU4-35P, and RNU6-391P. Each is linked with BAALC-AS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BAALC-AS2-to-partner and partner-to-BAALC-AS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3912 grouped by BAALC-AS2-low versus BAALC-AS2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAALC-AS2→partner) and Y-score (partner→BAALC-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3912 →	+0.565	+4.223	<.001	.003	3	1
UCEC	RNU4-35P →	+0.372	+4.038	<.001	.004	3	1
UCEC	RNU6-391P →	+0.423	+4.442	<.001	.007	3	1
UCEC	MIR147A →	+0.547	+6.167	<.001	<.001	3	1
UCEC	GPAA1P1 →	+0.324	+4.267	<.001	.009	3	1
UCEC	ATP5F1AP7 →	+0.025	+4.267	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MIR3912 by BAALC-AS2 expression — UCEC

Explore this box plot interactively →