BAALC-AS2

Across TCGA pan-cancer cohorts, BAALC-AS2 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of BAALC-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where BAALC-AS2 RNA is repressed in tumor relative to normal tissue. In most cancer types BAALC-AS2 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KICH, and KIRP are the cancer types where BAALC-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BAALC-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	−0.531	<.001	12	view →
KICH	Female	II,III,IV	+2.575	<.001	8	view →
KIRP	All	II,III,IV	−0.407	.003	6	view →
BRCA	Female	All	−0.222	.001	4	view →
HNSC	Male	III,IV	+0.336	.001	2	view →
LUAD	Female	II,III,IV	−0.363	.033	1	view →
CHOL	Female	All	+0.283	.023	1	view →
LIHC	All	II,III,IV	+0.120	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

BAALC-AS2–KIRC

Open the KIRC breakdown →