RNA, U4 small nuclear 35, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU4-35P profile across patient tissues and cancer cell-line models. RNU4-35P expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in THYM. Among the 18 cancer types available for tumor–normal comparison, RNU4-35P is differentially expressed in 3, with the highest sampling consensus in KIRC. Additionally, RNU4-35P RNA expression shows 8,229 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight THYM, KIRC, and KIRP as cancer lineages where RNU4-35P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU4-35P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU4-35P survival associations across molecular data types. RNU4-35P RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU4-35P RNA expression–survival associations across cancer types. High RNU4-35P expression shows unfavorable associations in THYM, KICH, LGG, UVM, READ and CHOL. The THYM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THYM as the clearest survival context for RNU4-35P RNA expression.
This table summarizes RNU4-35P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for RNU4-35P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU4-35P shows lower tumor expression in THCA and higher tumor expression in KIRC and HNSC. The KIRC box plot shows higher RNU4-35P RNA expression in tumor versus normal tissue (log2 FC = +0.200, t-test p < 0.001).
This table shows molecular features associated with RNU4-35P in patient tissues and cancer cell lines. In patient samples, RNU4-35P shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set.
