B3GALT2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B3GALT2 mutation is significantly associated with the RNA expression of many other genes, with 3,222 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GALT2-associated genes across cancer lineages are H3P15, ELOCP20, and EEF1A1P40. Each is linked with B3GALT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both B3GALT2-to-partner and partner-to-B3GALT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H3P15 grouped by B3GALT2-low versus B3GALT2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GALT2→partner) and Y-score (partner→B3GALT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADH3P15 →+0.528+4.308<.001.00933
SKCMELOCP20 →+0.165+5.594<.001.00433
CESCEEF1A1P40 →+0.077+6.144<.001.00132
UCECLSP1P1 →+0.206+1.731.001.00332
COADUBE2V1P4 →+0.251+5.136<.001.00232
CESCTP53TG3GP →+0.695+5.103<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,222 associations by consensus.

H3P15 by B3GALT2 expression — COAD

Box plot of H3P15 in B3GALT2-low vs B3GALT2-high samples in COAD.

Explore this box plot interactively →

Exploration