H3P15

Q-omics provides the consensus-scored H3P15 profile across patient tissues and cancer cell-line models. H3P15 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in ACC. Additionally, H3P15 RNA expression shows 6,463 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight ACC, and STAD as cancer lineages where H3P15 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes H3P15 survival associations across molecular data types. H3P15 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

H3P15 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	UVM (54)	view →

This table ranks reproducible H3P15 RNA expression–survival associations across cancer types. High H3P15 expression shows unfavorable associations in ACC, UVM, KIRC, COAD, OV and SKCM. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for H3P15 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.114	0.892	<.001	54	view →
UVM	DFS	Tertile	All	0.071	0.746	<.001	54	view →
KIRC	OS	Tertile	All	0.487	0.657	<.001	51	view →
COAD	DFS	Tertile	II,III,IV	0.215	0.657	<.001	39	view →
OV	OS	Tertile	IV	0.059	0.759	.006	36	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	33	view →

Pink = unfavorable, green = favorable. all 9 lineages →

H3P15-ACC (OS)

Explore this curve interactively →