ATXN7L3

Across TCGA patient cohorts, ATXN7L3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,687 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ATXN7L3-associated genes across cancer lineages are PZP, EFTUD2, and BRCA1. Each is linked with ATXN7L3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATXN7L3-to-partner and partner-to-ATXN7L3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATXN7L3 versus PZP in UCEC, with a Pearson correlation of -0.21.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN7L3→partner) and Y-score (partner→ATXN7L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PZP →	-0.826	-0.239	.002	.004	3	3
LSCC	EFTUD2 →	+0.563	+0.433	<.001	<.001	3	3
LSCC	BRCA1 →	+0.859	+0.396	<.001	<.001	3	3
BRCA	TUBG1 →	+0.558	+0.321	.001	<.001	3	3
LSCC	VPS25 →	+0.556	+0.390	<.001	<.001	3	3
BRCA	SLC25A39 →	+0.649	+0.295	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,687 associations by consensus.

ATXN7L3 vs PZP — UCEC

Explore this scatter interactively →