ATXN1L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATXN1L mutation is significantly associated with the RNA expression of many other genes, with 5,373 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATXN1L-associated genes across cancer lineages are GNAI2P1, RN7SL248P, and MIR598. Each is linked with ATXN1L in more than 1 cancer types. Because this analysis shows association rather than direction, both ATXN1L-to-partner and partner-to-ATXN1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN1L→partner) and Y-score (partner→ATXN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCGNAI2P1 →+0.194+4.661<.001<.00132
CESCRN7SL248P →+0.080+5.584<.001.00132
CESCMIR598 →+0.517+4.016<.001.00132
ESCALINC00333 →+0.089+4.564<.001.00432
UCECADM →+0.755+1.700<.001.00132
UCECCOX15 →+0.468+1.807<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,373 associations by consensus.

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