G protein subunit alpha i2 pseudogene 1Genealiases: GNAI2A · GNAI2L
Q-omics provides the consensus-scored GNAI2P1 profile across patient tissues and cancer cell-line models. GNAI2P1 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in BLCA. Among the 18 cancer types available for tumor–normal comparison, GNAI2P1 is differentially expressed in 3, with the highest sampling consensus in COAD. Additionally, GNAI2P1 RNA expression shows 6,703 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight BLCA, COAD, and STAD as cancer lineages where GNAI2P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GNAI2P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GNAI2P1 survival associations across molecular data types. GNAI2P1 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GNAI2P1 RNA expression–survival associations across cancer types. High GNAI2P1 expression shows unfavorable associations in BRCA, CHOL, ACC, LAML and KIRP, but favorable associations in BLCA. The BLCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .004). Together, the overview and detailed table identify BLCA as the clearest survival context for GNAI2P1 RNA expression.
This table summarizes GNAI2P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for GNAI2P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GNAI2P1 shows higher tumor expression in COAD, ESCA and LIHC. The COAD box plot shows higher GNAI2P1 RNA expression in tumor versus normal tissue (log2 FC = +0.133, t-test p = .017).
This table shows molecular features associated with GNAI2P1 in patient tissues and cancer cell lines. In patient samples, GNAI2P1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
