ATP8B4

Across TCGA patient cohorts, ATP8B4 protein abundance is significantly associated with the RNA expression of many other genes, with 550 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATP8B4-associated genes across cancer lineages are PODXL2, C10orf95, and OLFM1. Each is linked with ATP8B4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP8B4-to-partner and partner-to-ATP8B4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP8B4 versus PODXL2 in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP8B4→partner) and Y-score (partner→ATP8B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PODXL2 →	-1.785	-0.884	.008	.008	3	1
LSCC	C10orf95 →	+0.145	+0.841	.004	.005	3	1
LSCC	OLFM1 →	+3.134	+0.743	<.001	.001	3	1
LSCC	TIMM10B →	-0.582	-0.684	.006	.003	3	1
LSCC	HORMAD1 →	+2.280	+0.655	.002	.006	3	1
LSCC	FRMPD2B →	+1.150	+1.017	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 550 associations by consensus.

ATP8B4 vs PODXL2 — LSCC

Explore this scatter interactively →