chromosome 10 open reading frame 95Genealiases: []
Q-omics provides the consensus-scored C10orf95 profile across patient tissues and cancer cell-line models. C10orf95 expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, C10orf95 is differentially expressed in 14, with the highest sampling consensus in KIRC. Additionally, C10orf95 RNA expression shows 20,078 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ACC, KIRC, and UVM as cancer lineages where C10orf95 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for C10orf95 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes C10orf95 survival associations across molecular data types. C10orf95 RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible C10orf95 RNA expression–survival associations across cancer types. High C10orf95 expression shows unfavorable associations in ACC and THCA, but favorable associations in BLCA, MESO, SCLC and UCS. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for C10orf95 RNA expression.
This table summarizes C10orf95 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14, while mass-spec protein shows differences in 1. The strongest signals are observed in KIRC for RNA and LUAD for protein.
This table ranks reproducible tumor–normal expression differences for C10orf95. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. C10orf95 shows lower tumor expression in KIRC, LUSC and KICH and higher tumor expression in COAD, STAD and BLCA. The KIRC box plot shows higher C10orf95 RNA expression in normal versus tumor tissue (log2 FC = −0.800, t-test p < 0.001).
This table shows molecular features associated with C10orf95 in patient tissues and cancer cell lines. In patient samples, C10orf95 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, C10orf95 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Leukemia, while CRISPR and shRNA rows add functional-dependency signals in BONE and LUNG_SCLC.
