C10orf95

Across TCGA pan-cancer cohorts, C10orf95 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of C10orf95’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where C10orf95 RNA is repressed in tumor relative to normal tissue. In most cancer types C10orf95 is over-expressed in tumor, although a few such as KIRC and LUSC show the opposite, repressed pattern.

KIRC, COAD, and STAD are the cancer types where C10orf95 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C10orf95 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.800	<.001	12	view →
COAD	Female	II,III,IV	+0.755	<.001	10	view →
STAD	Male	II,III,IV	+1.200	<.001	9	view →
BLCA	Male	All	+0.799	.001	9	view →
LUSC	Female	II,III,IV	−1.904	<.001	8	view →
KICH	Male	All	−1.235	<.001	8	view →
LIHC	Female	All	+0.255	<.001	8	view →
THCA	Female	II,III,IV	+1.169	<.001	7	view →
BRCA	All	III,IV	+0.469	<.001	6	view →
CHOL	All	All	+1.417	<.001	5	view →
LUAD	All	All	−0.584	.002	3	view →
READ	Female	All	+0.752	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

C10orf95–KIRC

Open the KIRC breakdown →