ATP5F1C

Across TCGA patient cohorts, ATP5F1C mutation is significantly associated with the RNA expression of many other genes, with 2,258 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5F1C-associated genes across cancer lineages are RNA5SP93, FAM197Y5, and MIR549A. Each is linked with ATP5F1C in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP5F1C-to-partner and partner-to-ATP5F1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP93 grouped by ATP5F1C-low versus ATP5F1C-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1C→partner) and Y-score (partner→ATP5F1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP93 →	+0.938	+5.824	<.001	.001	3	3
STAD	FAM197Y5 →	+0.063	+5.274	.004	.006	3	2
LUSC	MIR549A →	+0.349	+4.625	<.001	.008	3	2
COAD	RNU7-80P →	+1.217	+4.308	<.001	.009	3	2
COAD	MIR103A1 →	+0.950	+5.136	<.001	.002	3	2
COAD	RNU6-661P →	+0.700	+4.666	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,258 associations by consensus.

RNA5SP93 by ATP5F1C expression — COAD

Explore this box plot interactively →