ATOH7

Across TCGA patient cohorts, ATOH7 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATOH7-associated genes across cancer lineages are RNA5SP414, MIR6500, and IGHV4-4. Each is linked with ATOH7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATOH7-to-partner and partner-to-ATOH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP414 grouped by ATOH7-low versus ATOH7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATOH7→partner) and Y-score (partner→ATOH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP414 →	+0.606	+3.255	.004	.003	3	1
UCEC	MIR6500 →	+0.365	+3.396	.004	.006	3	1
UCEC	IGHV4-4 →	+1.267	+3.953	.001	.002	3	1
UCEC	MIR4499 →	+0.349	+3.344	.006	.007	3	1
UCEC	IGHV3OR16-9 →	+0.789	+3.763	.001	.002	3	1
COAD	MIR1913 →	+0.530	+5.516	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

RNA5SP414 by ATOH7 expression — UCEC

Explore this box plot interactively →