ATOH7

Across TCGA pan-cancer cohorts, ATOH7 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ATOH7 data layer compared with 3 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher ATOH7 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ATOH7 expression acts as an unfavorable survival marker, although some lineages such as OV and UCS show a favorable association.

OV, UCS, and ACC are the cancer types where ATOH7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	All	0.361	0.272	.002	62	view →
UCS	DFS	Tertile	II,III,IV	0.643	0.186	.002	50	view →
ACC	DFS	Median	III,IV	0.093	0.600	<.001	41	view →
SCLC	DFS	Median	III,IV	0.316	0.694	.004	25	view →
KIRP	OS	Tertile	All	1.000	0.501	.001	18	view →
MESO	OS	Tertile	IV	0.824	0.394	.020	15	view →
ESCA	DFS	Tertile	All	0.421	1.000	.012	15	view →
LIHC	OS	Tertile	III,IV	0.195	0.638	.013	13	view →
LGG	DFS	Median	All	0.868	0.798	.006	9	view →
PAAD	OS	Quartile	II,III,IV	0.455	0.735	.023	9	view →
THYM	DFS	Median	All	0.973	0.740	.004	8	view →
HNSC	DFS	Tertile	IV	0.679	0.395	.016	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ATOH7–OV (OS)

Open the OV breakdown →