Across TCGA patient cohorts, ATF6B mutation is significantly associated with the RNA expression of many other genes, with 904 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATF6B-associated genes across cancer lineages are RNU6-693P, RNA5SP69, and RPL5P31. Each is linked with ATF6B in more than 1 cancer types. Because this analysis shows association rather than direction, both ATF6B-to-partner and partner-to-ATF6B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF6B→partner) and Y-score (partner→ATF6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RNU6-693P →	+0.343	+7.977	<.001	.007	3	2
LIHC	RNA5SP69 →	+0.714	+4.174	<.001	.009	3	2
COAD	RPL5P31 →	+0.139	+3.276	.004	.005	3	2
LIHC	OR2A12 →	+0.033	+5.305	<.001	.003	3	2
PRAD	RNU6-976P →	+0.323	+7.939	<.001	.008	3	2
COAD	OR6C2 →	+0.029	+4.225	.006	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 904 associations by consensus.

Exploration

ATF6B survival (RNA) · tumor vs normal (RNA) · all ATF6B data types