Q-omics provides the consensus-scored RPL5P31 profile across patient tissues and cancer cell-line models. RPL5P31 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, RPL5P31 is differentially expressed in 2, with the highest sampling consensus in HNSC. Additionally, RPL5P31 RNA expression shows 7,011 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRC, HNSC, and TGCT as cancer lineages where RPL5P31 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPL5P31 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPL5P31 survival associations across molecular data types. RPL5P31 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPL5P31 RNA expression–survival associations across cancer types. High RPL5P31 expression shows unfavorable associations in KIRC, MESO, ACC, STAD and DLBC, but favorable associations in TGCT. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for RPL5P31 RNA expression.
This table summarizes RPL5P31 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for RPL5P31. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPL5P31 shows lower tumor expression in KICH and higher tumor expression in HNSC. The HNSC box plot shows higher RPL5P31 RNA expression in tumor versus normal tissue (log2 FC = +0.135, t-test p = .028).
This table shows molecular features associated with RPL5P31 in patient tissues and cancer cell lines. In patient samples, RPL5P31 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
