Across TCGA pan-cancer cohorts, RPL5P31 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL5P31’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPL5P31 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL5P31 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC and KICH are the cancer types where RPL5P31 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL5P31 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.135	.028	4	view →
KICH	Female	All	−0.040	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RPL5P31 RNA expression & survival · all RPL5P31 data types