Across TCGA patient cohorts, ASB12 mutation is significantly associated with the RNA expression of many other genes, with 1,313 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB12-associated genes across cancer lineages are FAM47DP, PINCR, and BNIP3P2. Each is linked with ASB12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB12-to-partner and partner-to-ASB12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB12→partner) and Y-score (partner→ASB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	FAM47DP →	+0.024	+3.855	.004	.008	3	2
READ	PINCR →	+0.192	+4.142	<.001	.004	3	2
READ	BNIP3P2 →	+0.448	+4.179	<.001	.003	3	2
READ	BNIP3P6 →	+0.284	+4.341	<.001	.007	3	2
LGG	KRTAP20-3 →	+0.174	+7.977	<.001	.007	3	2
LGG	RNU6-1211P →	+0.388	+7.977	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,313 associations by consensus.

Exploration

ASB12 survival (RNA) · tumor vs normal (RNA) · all ASB12 data types