ARL14EP

Across TCGA patient cohorts, ARL14EP mutation is significantly associated with the RNA expression of many other genes, with 78 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL14EP-associated genes across cancer lineages are MTND3P13, POMPP1, and RNU6-871P. Each is linked with ARL14EP in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL14EP-to-partner and partner-to-ARL14EP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND3P13 grouped by ARL14EP-low versus ARL14EP-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL14EP→partner) and Y-score (partner→ARL14EP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MTND3P13 →	+0.255	+5.893	<.001	.002	3	2
CESC	POMPP1 →	+0.077	+5.837	<.001	.001	3	2
CESC	RNU6-871P →	+0.296	+4.812	<.001	.006	3	2
UCEC	VN1R93P →	+0.334	+3.936	<.001	.005	3	2
UCEC	OR2AP1 →	+0.080	+4.267	.001	.009	3	2
UCEC	TUBAP10 →	+0.096	+4.223	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 78 associations by consensus.

MTND3P13 by ARL14EP expression — COAD

Explore this box plot interactively →