ARHGAP11A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARHGAP11A mutation is significantly associated with the RNA expression of many other genes, with 4,054 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP11A-associated genes across cancer lineages are PPIAP38, GLUD1P4, and ANKRD20A6P. Each is linked with ARHGAP11A in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGAP11A-to-partner and partner-to-ARHGAP11A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP11A→partner) and Y-score (partner→ARHGAP11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPPIAP38 →+0.115+2.689.001.00834
LIHCGLUD1P4 →+0.082+5.463<.001<.00133
READANKRD20A6P →+0.193+4.925<.001.00433
LUADCOX6CP3 →+0.182+3.575<.001.00533
UCECAURKB →+0.634+2.223.001<.00133
UCECMIR34AHG →+0.396+2.223<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,054 associations by consensus.

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