peptidylprolyl isomerase A pseudogene 38Genealiases: []
Q-omics provides the consensus-scored PPIAP38 profile across patient tissues and cancer cell-line models. PPIAP38 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, PPIAP38 is differentially expressed in 2, with the highest sampling consensus in COAD. Additionally, PPIAP38 RNA expression shows 4,472 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UCEC, COAD, and STAD as cancer lineages where PPIAP38 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PPIAP38 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PPIAP38 survival associations across molecular data types. PPIAP38 RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PPIAP38 RNA expression–survival associations across cancer types. High PPIAP38 expression shows unfavorable associations in UCEC, MESO, OV, PCPG and DLBC, but favorable associations in KIRC. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for PPIAP38 RNA expression.
This table summarizes PPIAP38 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for PPIAP38. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PPIAP38 shows lower tumor expression in COAD and higher tumor expression in LUSC. The COAD box plot shows higher PPIAP38 RNA expression in normal versus tumor tissue (log2 FC = −0.167, t-test p < 0.001).
This table shows molecular features associated with PPIAP38 in patient tissues and cancer cell lines. In patient samples, PPIAP38 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
