PPIAP38

Across TCGA pan-cancer cohorts, PPIAP38 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated PPIAP38 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PPIAP38 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PPIAP38 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

UCEC, MESO, and OV are the cancer types where PPIAP38 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	0.592	0.864	<.001	120	view →
MESO	OS	Tertile	II,III,IV	0.215	0.595	<.001	108	view →
OV	OS	Tertile	II,III,IV	0.245	0.345	.003	72	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
PCPG	OS	Tertile	All	0.505	0.946	<.001	27	view →
KIRC	DFS	Tertile	All	0.928	0.597	.030	24	view →
UCS	OS	Tertile	IV	1.000	0.293	.035	18	view →
BLCA	OS	Tertile	IV	0.179	0.603	.006	18	view →
LIHC	DFS	Tertile	III,IV	0.095	0.337	.004	18	view →
LGG	OS	Median	All	0.966	0.841	<.001	14	view →
STAD	DFS	Quartile	III,IV	0.363	0.507	.029	11	view →
SKCM	OS	Tertile	All	0.726	0.880	.010	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

PPIAP38–UCEC (OS)

Open the UCEC breakdown →