Across TCGA patient cohorts, APOC4-APOC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,095 significant associations in total. LGG shows the largest number of these associations.

The most reproducible APOC4-APOC2-associated GO terms across cancer lineages are Phagocytosis, Phagocytosis, engulfment, and Regulation of leukocyte proliferation. Each is linked with APOC4-APOC2 in more than 25 cancer types. Because this analysis shows association rather than direction, both APOC4-APOC2-to-partner and partner-to-APOC4-APOC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APOC4-APOC2→partner) and Y-score (partner→APOC4-APOC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Phagocytosis →	+0.044	+0.178	<.001	<.001	3	26
KIRP	Phagocytosis, engulfment →	+0.052	+0.380	<.001	<.001	3	26
ESCA	Regulation of leukocyte proliferation →	+0.047	+0.177	<.001	<.001	3	26
LGG	Regulation of phagocytosis →	+0.050	+0.525	<.001	<.001	3	26
LGG	Myeloid leukocyte activation →	+0.040	+0.550	<.001	<.001	3	26
DLBC	Amyloid-beta clearance →	+0.088	+0.556	.007	.002	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,095 associations by consensus.

Exploration

APOC4-APOC2 survival (RNA) · tumor vs normal (RNA) · all APOC4-APOC2 data types