APBA3

Across TCGA patient cohorts, APBA3 mutation is significantly associated with the RNA expression of many other genes, with 1,859 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible APBA3-associated genes across cancer lineages are MIR128-1, AQP7P5, and RNA5SP387. Each is linked with APBA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both APBA3-to-partner and partner-to-APBA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR128-1 grouped by APBA3-low versus APBA3-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APBA3→partner) and Y-score (partner→APBA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	MIR128-1 →	+0.433	+5.345	<.001	.005	3	2
SKCM	AQP7P5 →	+0.062	+4.132	.007	<.001	3	2
CESC	RNA5SP387 →	+0.462	+5.342	<.001	.002	3	2
UCEC	LINC01730 →	+0.425	+3.624	<.001	.001	3	2
UCEC	SENP3-EIF4A1 →	+0.128	+2.382	<.001	.003	3	2
HNSC	TRAV8-7 →	+0.161	+3.716	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,859 associations by consensus.

MIR128-1 by APBA3 expression — SARC

Explore this box plot interactively →