Q-omics provides the consensus-scored AQP7P5 profile across patient tissues and cancer cell-line models. AQP7P5 expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, AQP7P5 is differentially expressed in 4, with the highest sampling consensus in BRCA. Additionally, AQP7P5 RNA expression shows 5,558 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, BRCA, and STAD as cancer lineages where AQP7P5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for AQP7P5 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes AQP7P5 survival associations across molecular data types. AQP7P5 RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible AQP7P5 RNA expression–survival associations across cancer types. High AQP7P5 expression shows unfavorable associations in KIRC, LIHC, LUAD, KIRP and PAAD. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for AQP7P5 RNA expression.
This table summarizes AQP7P5 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for AQP7P5. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. AQP7P5 shows lower tumor expression in BRCA, ESCA, KIRP and STAD. The BRCA box plot shows higher AQP7P5 RNA expression in normal versus tumor tissue (log2 FC = −0.099, t-test p < 0.001).
This table shows molecular features associated with AQP7P5 in patient tissues and cancer cell lines. In patient samples, AQP7P5 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
