ANTXR2

Across TCGA patient cohorts, ANTXR2 mutation is significantly associated with the RNA expression of many other genes, with 2,878 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANTXR2-associated genes across cancer lineages are RN7SL248P, RNA5SP411, and RNU1-17P. Each is linked with ANTXR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANTXR2-to-partner and partner-to-ANTXR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by ANTXR2-low versus ANTXR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANTXR2→partner) and Y-score (partner→ANTXR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.041	+2.593	<.001	.003	3	2
LUSC	RNA5SP411 →	+0.787	+4.733	<.001	.004	3	2
UCEC	RNU1-17P →	+0.208	+2.198	<.001	<.001	3	2
UCEC	RNA5SP369 →	+0.282	+1.845	<.001	<.001	3	2
UCEC	MTATP6P21 →	+0.194	+1.619	<.001	.002	3	2
CESC	MTCYBP45 →	+0.224	+4.934	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,878 associations by consensus.

RN7SL248P by ANTXR2 expression — UCEC

Explore this box plot interactively →