ANKRD9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD9 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD9-associated genes across cancer lineages are RNU4-58P, RNU6-371P, and RNA5SP239. Each is linked with ANKRD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD9-to-partner and partner-to-ANKRD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-58P grouped by ANKRD9-low versus ANKRD9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD9→partner) and Y-score (partner→ANKRD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU4-58P →+0.524+5.133<.001.00832
COADRNU6-371P →+0.596+7.741<.001.00931
COADRNA5SP239 →+0.623+7.741<.001.00931
COADRN7SL584P →+1.423+7.741<.001.00931
COADRN7SKP260 →+0.239+7.741<.001.00931
COADZNF519P3 →+0.039+7.741<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

RNU4-58P by ANKRD9 expression — UCEC

Box plot of RNU4-58P in ANKRD9-low vs ANKRD9-high samples in UCEC.

Explore this box plot interactively →

Exploration