ANKRD34A

Across TCGA cell cohorts, ANKRD34A mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANKRD34A-associated genes across cancer lineages are BTBD16, PRDM14, and UGT2B4. Each is linked with ANKRD34A in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD34A-to-partner and partner-to-ANKRD34A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTBD16 grouped by ANKRD34A-low versus ANKRD34A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD34A→partner) and Y-score (partner→ANKRD34A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BTBD16 →	+0.092	+3.959	<.001	.005	3	1
BLOOD_Leukemia	PRDM14 →	+0.005	+3.705	.007	.007	3	1
BLOOD_Leukemia	UGT2B4 →	+0.058	+3.855	<.001	.007	3	1
BLOOD_Leukemia	TEX48 →	+0.030	+4.060	<.001	.003	3	1
OVARY	FHL5 →	+0.014	+3.700	<.001	.005	3	1
OVARY	GPR148 →	+0.047	+4.095	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

BTBD16 by ANKRD34A expression — BLOOD_Leukemia

Explore this box plot interactively →