ANKRD34A

Across TCGA pan-cancer cohorts, ANKRD34A RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ANKRD34A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ANKRD34A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ANKRD34A is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

KIRP, LUAD, and LIHC are the cancer types where ANKRD34A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANKRD34A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	+0.597	.001	8	view →
LUAD	All	III,IV	+0.546	<.001	8	view →
LIHC	Female	II,III,IV	+0.476	<.001	8	view →
THCA	Male	All	−0.423	<.001	7	view →
KIRC	Male	All	+0.233	<.001	7	view →
BLCA	Female	IV	+0.796	.011	4	view →
KICH	Female	All	−0.595	<.001	4	view →
LUSC	All	All	+0.220	.010	3	view →
CHOL	All	All	+0.576	.017	2	view →
UCEC	All	All	−0.445	.036	2	view →
BLCA	Male	IV	−1.287	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

ANKRD34A–KIRP

Open the KIRP breakdown →