ANKRD30A

Across TCGA patient cohorts, ANKRD30A mutation is significantly associated with the RNA expression of many other genes, with 5,671 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD30A-associated genes across cancer lineages are PPM1G, SAAL1, and ACP1. Each is linked with ANKRD30A in more than 5 cancer types. Because this analysis shows association rather than direction, both ANKRD30A-to-partner and partner-to-ANKRD30A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPM1G grouped by ANKRD30A-low versus ANKRD30A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD30A→partner) and Y-score (partner→ANKRD30A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPM1G →	+0.592	+3.343	<.001	.005	3	6
HNSC	SAAL1 →	+0.426	+3.468	.008	.002	3	6
SKCM	ACP1 →	+0.227	+0.886	.001	.006	3	6
UCEC	RCC1 →	+0.326	+1.847	.001	<.001	3	5
LUAD	KPNA2 →	+0.540	+2.044	.001	<.001	3	5
UCEC	JPT1 →	+0.367	+1.595	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,671 associations by consensus.

PPM1G by ANKRD30A expression — BRCA

Explore this box plot interactively →