ANKRD30A

Across TCGA pan-cancer cohorts, ANKRD30A RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ANKRD30A data layer compared with 10 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ANKRD30A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ANKRD30A expression acts as an unfavorable survival marker, although some lineages such as BRCA and LAML show a favorable association.

KIRC, HNSC, and BRCA are the cancer types where ANKRD30A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.522	0.733	<.001	165	view →
HNSC	OS	Tertile	III,IV	0.377	0.728	<.001	66	view →
BRCA	DFS	Tertile	III,IV	0.943	0.802	<.001	61	view →
SCLC	OS	Tertile	IV	0.137	0.548	.004	36	view →
BLCA	OS	Tertile	IV	0.458	0.632	.007	31	view →
UCS	DFS	Median	IV	0.438	0.812	.033	30	view →
READ	OS	Tertile	IV	0.111	0.893	<.001	27	view →
UVM	OS	Tertile	All	0.248	0.769	.007	24	view →
LIHC	OS	Tertile	All	0.685	0.818	.006	21	view →
LAML	DFS	Tertile	All	0.696	0.328	.014	20	view →
MESO	OS	Quartile	II,III,IV	0.197	0.651	.016	18	view →
GBM	OS	Tertile	All	0.273	0.446	.007	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ANKRD30A–KIRC (OS)

Open the KIRC breakdown →