ADAM15

Across TCGA patient cohorts, ADAM15 mutation is significantly associated with the RNA expression of many other genes, with 2,359 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAM15-associated genes across cancer lineages are RN7SL20P, SEPTIN14P19, and NPLP1. Each is linked with ADAM15 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADAM15-to-partner and partner-to-ADAM15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL20P grouped by ADAM15-low versus ADAM15-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM15→partner) and Y-score (partner→ADAM15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL20P →	+0.116	+3.038	.009	.008	3	3
HNSC	SEPTIN14P19 →	+0.056	+4.822	<.001	.006	3	2
READ	NPLP1 →	+0.291	+5.421	<.001	.005	3	2
BRCA	KRTAP9-1 →	+0.068	+4.162	<.001	.009	3	2
UCEC	DONSON →	+0.495	+3.008	.001	<.001	3	2
UCEC	GFI1 →	+0.473	+2.684	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,359 associations by consensus.

RN7SL20P by ADAM15 expression — BLCA

Explore this box plot interactively →