ABHD4

Across TCGA patient cohorts, ABHD4 mutation is significantly associated with the RNA expression of many other genes, with 3,757 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD4-associated genes across cancer lineages are USP12PY, NTAN1, and ATRIP. Each is linked with ABHD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD4-to-partner and partner-to-ABHD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP12PY grouped by ABHD4-low versus ABHD4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD4→partner) and Y-score (partner→ABHD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	USP12PY →	+0.052	+4.133	.006	.001	3	2
UCEC	NTAN1 →	+0.554	+2.906	<.001	<.001	3	2
UCEC	ATRIP →	+0.099	+2.093	<.001	.004	3	2
UCEC	CD99P1 →	+0.402	+2.269	<.001	<.001	3	2
SKCM	RNU7-119P →	+0.250	+4.039	<.001	.009	3	2
UCEC	ZNF234 →	+0.321	+1.857	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,757 associations by consensus.

USP12PY by ABHD4 expression — COAD

Explore this box plot interactively →