ABHD4

Across TCGA cell cohorts, ABHD4 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ABHD4-associated genes across cancer lineages are OR52N5, OR56B1, and OR6C70. Each is linked with ABHD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD4-to-partner and partner-to-ABHD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52N5 grouped by ABHD4-low versus ABHD4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD4→partner) and Y-score (partner→ABHD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR52N5 →	+0.171	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR56B1 →	+0.048	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR6C70 →	+0.486	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	KRTAP22-2 →	+0.256	+5.228	<.001	.005	3	1
BLOOD_Leukemia	C6 →	+0.201	+4.922	<.001	.009	3	1
BLOOD_Lymphoma	FSHB →	+0.012	+5.247	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OR52N5 by ABHD4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →