ABHD12B

Across TCGA cell cohorts, ABHD12B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ABHD12B-associated genes across cancer lineages are POM121L12, C10orf71, and GCGR. Each is linked with ABHD12B in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD12B-to-partner and partner-to-ABHD12B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POM121L12 grouped by ABHD12B-low versus ABHD12B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD12B→partner) and Y-score (partner→ABHD12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	POM121L12 →	+0.030	+6.266	<.001	<.001	3	1
CNS	C10orf71 →	+0.016	+4.981	<.001	.008	3	1
LARGE_INTESTINE	GCGR →	+0.128	+3.584	.008	.006	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

POM121L12 by ABHD12B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →