ABCC10

Across TCGA patient cohorts, ABCC10 protein abundance is significantly associated with the RNA expression of many other genes, with 7,764 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ABCC10-associated genes across cancer lineages are LIG1, CDC25C, and SPDL1. Each is linked with ABCC10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCC10-to-partner and partner-to-ABCC10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCC10 versus LIG1 in BRCA, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC10→partner) and Y-score (partner→ABCC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LIG1 →	-0.528	-0.415	<.001	<.001	3	3
LUAD	CDC25C →	-0.606	-0.275	<.001	<.001	3	3
LSCC	SPDL1 →	-0.470	-0.249	.005	.008	3	3
CCRCC	RARS1 →	-0.445	-0.601	.003	.004	3	2
LUAD	RFC3 →	-0.482	-0.374	<.001	<.001	3	2
CCRCC	LARS1 →	-0.567	-0.554	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,764 associations by consensus.

ABCC10 vs LIG1 — BRCA

Explore this scatter interactively →