ABCC10

Across TCGA pan-cancer cohorts, ABCC10 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of ABCC10’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ABCC10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ABCC10 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, COAD, and LIHC are the cancer types where ABCC10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ABCC10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.895	<.001	12	view →
COAD	All	IV	+1.142	<.001	11	view →
LIHC	Female	II,III,IV	+1.705	<.001	9	view →
LUAD	All	III,IV	+0.740	<.001	9	view →
STAD	Male	II,III,IV	+1.255	<.001	8	view →
KICH	Female	All	−1.002	<.001	6	view →
KIRP	All	IV	+0.905	.002	6	view →
LUSC	Female	All	+0.846	<.001	6	view →
BLCA	All	All	+0.546	.006	6	view →
UCEC	All	All	+0.523	<.001	6	view →
CHOL	Male	All	+2.723	<.001	5	view →
READ	Female	All	+1.108	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

ABCC10–HNSC

Open the HNSC breakdown →