ABCC10

Across TCGA pan-cancer cohorts, ABCC10 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ABCC10 data layer compared with 6 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher ABCC10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ABCC10 expression acts as an unfavorable survival marker, although some lineages such as SCLC and THYM show a favorable association.

MESO, KIRC, and ACC are the cancer types where ABCC10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	II,III,IV	0.243	0.497	<.001	110	view →
KIRC	OS	Median	All	0.558	0.739	<.001	96	view →
ACC	DFS	Median	All	0.424	0.728	<.001	65	view →
LGG	DFS	Median	All	0.638	0.831	<.001	52	view →
LIHC	OS	Median	All	0.710	0.838	<.001	52	view →
SKCM	DFS	Quartile	III,IV	0.332	0.775	<.001	30	view →
SCLC	DFS	Quartile	II,III,IV	0.724	0.362	.017	29	view →
THYM	DFS	Quartile	II,III,IV	0.949	0.391	.004	27	view →
UCS	OS	Median	III,IV	0.672	0.260	.001	24	view →
COAD	DFS	Quartile	All	0.636	0.840	.007	20	view →
KIRP	DFS	Quartile	II,III,IV	0.907	0.581	.008	15	view →
SARC	OS	Tertile	All	0.439	0.772	.009	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ABCC10–MESO (OS)

Open the MESO breakdown →