ABCC10

Across TCGA patient cohorts, ABCC10 mutation is significantly associated with the RNA expression of many other genes, with 3,000 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCC10-associated genes across cancer lineages are PABPC1P5, RN7SL341P, and LINC00428. Each is linked with ABCC10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCC10-to-partner and partner-to-ABCC10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PABPC1P5 grouped by ABCC10-low versus ABCC10-high in OV.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC10→partner) and Y-score (partner→ABCC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PABPC1P5 →	+0.030	+3.510	<.001	.008	3	3
OV	RN7SL341P →	+0.081	+4.177	.003	.009	3	3
LGG	LINC00428 →	+0.147	+5.960	<.001	.001	3	3
HNSC	RNU6-737P →	+0.230	+5.351	<.001	.002	3	3
SKCM	SNRPBP1 →	+0.066	+1.675	<.001	.001	3	3
UCEC	TUBGCP5 →	+0.289	+1.858	.004	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,000 associations by consensus.

PABPC1P5 by ABCC10 expression — OV

Explore this box plot interactively →