ABCC10

Across TCGA cell cohorts, ABCC10 mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ABCC10-associated genes across cancer lineages are OR6V1, OR6K6, and HOOK1. Each is linked with ABCC10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCC10-to-partner and partner-to-ABCC10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6V1 grouped by ABCC10-low versus ABCC10-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC10→partner) and Y-score (partner→ABCC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR6V1 →	+0.014	+4.189	<.001	.002	3	3
LUNG_NSCLC_LUAD	OR6K6 →	+0.012	+4.681	<.001	.003	3	2
SKIN	HOOK1 →	+1.509	+3.184	<.001	.007	3	2
SOFT_TISSUE	TAS1R2 →	+0.006	+5.369	<.001	.004	3	1
SOFT_TISSUE	KRT26 →	+0.015	+4.930	.006	.008	3	1
SOFT_TISSUE	KRTAP10-10 →	+0.023	+5.977	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

OR6V1 by ABCC10 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →