ABCB1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABCB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,619 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABCB1-associated proteins across cancer lineages are CNRIP1, ADD3, and CAVIN2. Each is linked with ABCB1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ABCB1-to-partner and partner-to-ABCB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCB1 versus CNRIP1 in OV, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB1→partner) and Y-score (partner→ABCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCNRIP1 →+0.722+0.518<.001<.00138
BRCAADD3 →+0.478+0.710<.001<.00137
UCECCAVIN2 →+0.760+0.641<.001<.00137
UCECDPT →+0.721+0.893.002<.00137
OVEPB41L3 →+0.795+0.787<.001<.00137
UCECHAAO →+0.741+1.006<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,619 associations by consensus.

ABCB1 vs CNRIP1 — OV

Per-sample scatter of ABCB1 vs CNRIP1 in OV (Pearson r = 0.36).

Explore this scatter interactively →

Exploration