Olfactory behavior

Across TCGA patient cohorts, RNA activity of the Olfactory behavior pathway is significantly associated with the RNA expression of multiple genes, with the HNSC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are LINC01934, RPL10, and CNTN3, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Olfactory behavior activity versus LINC01934 in HNSC (Pearson r = -0.04).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC01934 →	-0.386	-0.554	.003	.005	3	4
OV	RPL10 →	-0.448	-0.526	.007	<.001	3	3
GBM	CNTN3 →	+0.956	+0.406	<.001	<.001	3	3
GBM	LRRC4B →	+0.613	+0.508	.008	.004	3	3
GBM	TMCO4 →	-0.508	-0.423	.002	.005	3	3
GBM	PDZRN4 →	+0.881	+0.464	.006	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0042048 vs LINC01934 — HNSC

Explore this scatter interactively →