Acylglycerol transport

pathway activity — cross-omics
GO:0034196Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Acylglycerol transport pathway is significantly associated with the protein abundance of multiple proteins, with the LSCC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are GALM, TAOK3, and WIPF1, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Acylglycerol transport activity versus GALM in LSCC (Pearson r = 0.28).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCGALM →+0.369+0.064.002.00536
LSCCTAOK3 →+0.351+0.097<.001<.00135
LSCCWIPF1 →+0.364+0.093<.001<.00135
LSCCGIMAP7 →+0.577+0.073<.001.00135
HNSCGIMAP8 →+0.535+0.118<.001<.00135
LSCCHCLS1 →+0.509+0.081<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0034196 vs GALM — LSCC

Per-sample scatter of Acylglycerol transport activity vs GALM in LSCC.

Explore this scatter interactively →

Exploration