Chemosensory behavior

Across TCGA cell cohorts, RNA activity of the Chemosensory behavior pathway is significantly associated with the RNA expression of multiple genes, with the STOMACH cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are CARD6, RNPEP, and BMP2, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, CARD6 grouped by Chemosensory behavior-low versus -high activity in STOMACH.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CARD6 →	-1.516	-0.933	.001	.005	3	4
BONE	RNPEP →	-0.997	-1.778	.006	<.001	3	4
LUNG_SCLC	BMP2 →	-2.308	-1.412	.002	.001	3	4
LUNG_SCLC	RNF187 →	-0.834	-1.202	.003	<.001	3	4
LUNG_SCLC	TMEM150C →	-2.415	-1.084	.003	.009	3	4
PANCREAS	CAP2 →	+2.112	+1.260	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

CARD6 by Chemosensory behavior activity — STOMACH

Explore this box plot interactively →