Ventricular compact myocardium morphogenesis

Across TCGA cell cohorts, RNA activity of the Ventricular compact myocardium morphogenesis pathway is significantly associated with the RNA expression of multiple genes, with the OVARY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are NUP85, ARG2, and MRPS27, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, NUP85 grouped by Ventricular compact myocardium morphogenesis-low versus -high activity in OVARY.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	NUP85 →	+0.677	+1.192	.007	.006	3	5
UPPER_AERODIGESTIVE_TRACT	ARG2 →	-1.496	-1.280	.004	<.001	3	4
LUNG_SCLC	MRPS27 →	+1.295	+1.372	.001	.002	3	4
LIVER	PIGT →	-0.636	-1.436	.003	.001	3	3
LUNG_NSCLC_LUSC	ZMAT5 →	+0.846	+1.240	.003	.002	3	3
LUNG_NSCLC_LUSC	SMURF2 →	+1.698	+1.189	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

NUP85 by Ventricular compact myocardium morphogenesis activity — OVARY

Explore this box plot interactively →