ZYX

Across TCGA cell cohorts, ZYX RNA expression is significantly associated with the RNA expression of many other genes, with 12,704 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZYX-associated genes across cancer lineages are PDLIM7, FLNA, and CD151. Each is linked with ZYX in more than 15 cancer types. Because this analysis shows association rather than direction, both ZYX-to-partner and partner-to-ZYX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZYX versus PDLIM7 in BONE, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZYX→partner) and Y-score (partner→ZYX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	PDLIM7 →	+2.135	+2.012	<.001	<.001	3	16
LIVER	FLNA →	+2.355	+1.585	<.001	<.001	3	16
BONE	CD151 →	+2.231	+1.943	<.001	<.001	3	15
BLOOD_Lymphoma	TPM4 →	+1.751	+2.782	<.001	<.001	3	14
LIVER	PPP1R18 →	+2.632	+1.594	<.001	<.001	3	14
LUNG_NSCLC_LUSC	SH3BGRL3 →	+2.100	+1.721	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,704 associations by consensus.

ZYX vs PDLIM7 — BONE

Explore this scatter interactively →