ZYX

Across TCGA cell cohorts, ZYX RNA expression is significantly associated with the go_rna of many other GO terms, with 6,398 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZYX-associated GO terms across cancer lineages are Positive regulation of cytoskeleton organization, Positive regulation of actin filament bundle assembly, and Positive regulation of supramolecular fiber organization. Each is linked with ZYX in more than 15 cancer types. Because this analysis shows association rather than direction, both ZYX-to-partner and partner-to-ZYX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoskeleton organization grouped by ZYX-low versus ZYX-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZYX→partner) and Y-score (partner→ZYX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of cytoskeleton organization →	+0.077	+1.431	.001	.001	3	16
BONE	Positive regulation of actin filament bundle assembly →	+0.169	+1.296	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Positive regulation of supramolecular fiber organization →	+0.086	+1.199	<.001	.004	3	15
BONE	Regulation of cell-matrix adhesion →	+0.143	+1.560	<.001	<.001	3	15
BONE	Regulation of proteolysis →	+0.113	+1.517	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Wound healing →	+0.125	+2.538	.005	.008	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,398 associations by consensus.

Positive regulation of cytoskeleton organization by ZYX expression — LIVER

Explore this box plot interactively →