Across TCGA patient cohorts, ZYG11A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,247 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZYG11A-associated proteins across cancer lineages are TPX2, TPX2_S486, and PDS5A_T1208. Each is linked with ZYG11A in more than 4 cancer types. Because this analysis shows association rather than direction, both ZYG11A-to-partner and partner-to-ZYG11A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZYG11A→partner) and Y-score (partner→ZYG11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TPX2 →	+0.797	+1.036	<.001	<.001	3	5
LUAD	TPX2_S486 →	+1.334	+1.141	.001	.002	3	5
BRCA	PDS5A_T1208 →	+0.615	+0.896	<.001	<.001	3	5
BRCA	DDX49 →	+0.251	+0.659	.002	<.001	3	5
LUAD	UFD1_S247 →	+0.679	+0.723	.001	.007	3	4
BRCA	WDR75 →	+0.291	+0.695	.002	.004	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,247 associations by consensus.

Exploration

ZYG11A survival (RNA) · tumor vs normal (RNA) · all ZYG11A data types